Atherosclerosis Development Concept Map
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Atherosclerosis Development Concept Map

Atherosclerosis development and its consequencesPrenatal risk factorsPostnatal risk factorsMother was a smoker during pregnancyFather died from a heart attack (Family history)Early birth weightPotential genetic predispositionHeavy smokerHyperlipidaemiaModerately obeseMajor risk factorsNeed to catch up weightToxins from cigarette smoke released(chemical insult)Change in blood constituentsRatio of total cholesterol to high density lipoproteins is 6.5Hypertension(high blood pressure)Other risk factorsAdvanced AgeDNA damageShear stress to endothelial cellsEndothelial cell damage(inflammatory)Increased permeabilityLipid infiltrationBuildup of atherosclerotic plaqueThrombusLeukocyte adhesionEndothelial cells produce endothelinInjured endothelial cells produce von Willebrand factorplatelet adhesion to exposed extracellular matrixExposed underlying connective tissue in basement membrane (Extracellular matrix)platelet activationPlatelets secrete thromboxane A, vasoactive amines, and ADPPromotes vasoconstriction and platelet aggregationActivates haemostasisPromotes haemostasisVasoconstrictionHypercoagulabilityChange in blood flowVirchow's triadHaemodynamic force of bloodEpigenetic reprogrammingIncreased risk of developing cardiavacular disease at an earky ageChange in vessel wallPathological damage in hospital testsLow output Heart failureDisease development due to atherosclerosisInadequate blood supply during resting (ischaemic)T-wave inversion in ECGSevere ischaemia and necrosis in heart muscleTroponin-1 and MB isotype of creatine kinasenecrosis of cardiomyocytesOrgan damageNuclear degradation via necrosis of right side of brainNecrosis of gut due to infarctionLung congestion due to presence of fibrous septa (indicates fluid buildup in lungs)Embolism of blood vessels in gut Loss of function to right side of bodyAngina pectorisTreatment and lifestyle changesMyocardial ischaemia
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publish time: 2021-05-23
Nicholas ngu

Here is a concept map about atherosclerosis development and its consequences. Atherosclerosis develops over the course of 50 years, beginning in the early teenage years. Arteriosclerosis occurs when the blood vessels that carry oxygen and nutrients from your heart to the rest of your body (arteries) become thick and stiff. Learn more details from this map, or try to make yours with ease.

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