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Schematic diagram of malignant transformation and osteogenic differentiation of hematopoietic stem cells

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Published on 2025-09-02
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This template provides an in-depth analysis of the bidirectional regulatory mechanism of malignant transformation and osteogenic differentiation of hematopoietic stem cells, covering the normal hematopoietic stem cell differentiation path (positive markers of nestin/Pix1/Moc1), osteoblast maturation stages (preosteoblast → osteoblast → osteocyte) and key molecules (type I collagen
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Leukemic microenvironment
Regulation of osteogenic differentiation
Malignant transformation of hematopoietic stem cells
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