This template provides an in-depth analysis of the bidirectional regulatory mechanism of malignant transformation and osteogenic differentiation of hematopoietic stem cells, covering the normal hematopoietic stem cell differentiation path (positive markers of nestin/Pix1/Moc1), osteoblast maturation stages (preosteoblast → osteoblast → osteocyte) and key molecules (type I collagen
Tag
Leukemic microenvironment
Regulation of osteogenic differentiation
Malignant transformation of hematopoietic stem cells