This cell junction template illustrates intercellular connections in animal tissues. Tight junctions with occludin and claudins create permeability barriers maintaining tissue compartmentalization. Adherens junctions featuring E-cadherin connect to actin cytoskeleton through catenins providing mechanical strength. Desmosomes with desmosomal cadherins anchor to intermediate filaments in stress-bearing tissues. Gap junctions formed by connexins permit direct cytoplasmic communication of ions and small molecules enabling electrical and metabolic coupling. Essential for histology education and understanding epithelial tissue organization.